Exchange 2007 referenced below should be Exchange 2010. Section Exchange ActiveSync without Exchange 2013.
4.For the Orange User, there are two possible scenarios: a.Orange User will connect to mail-region.contoso.com as his namespace endpoint. CAS2010 in Site2 will authenticate the user, do a service discovery, and determine that the mailbox is located within the local AD site and retrieve the necessary data from the Exchange 2010 Mailbox server.
b.Orange User will connect to mail.contoso.com as his namespace endpoint. CAS2010 in Site1 will authenticate the user, do a service discovery, and determine that the mailbox is located within Site2, which does contain an EAS ExternalURL. Assuming the device supports Autodiscover and is on a defined list of devices that supports the 451 redirect response, CAS2010 will issue a 451 response to the device, notifying the device it needs to use a new namespace, mail-region.contoso.com. CAS2010 in Site2 will then facilitate the request and retrieve the necessary data from the Exchange 2007 Mailbox server. If the device is not on the supported list, then CAS2010 in Site1 will proxy the request to CAS2010 in Site2
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