Can I Connect to O365 Security & Compliance center via powershell with MFA on?

The answer is Yes, the new module released for Exchange Online also includes a connection string for accessing the Security and Compliance Center.

 Connect to Exchange Online PowerShell using multi-factor authentication

This will install a ClickOnce app reference to launch the console with the module pre-loaded.

When you launch the console you will see this message:

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This PowerShell module allows you to connect to Exchange Online service.
To connect, use: Connect-EXOPSSession -UserPrincipalName <your UPN>
This PowerShell module allows you to connect Exchange Online Protection and Security & Compliance Center services also.
To connect, use: Connect-IPPSSession -UserPrincipalName <your UPN>

To get additional information, use: Get-Help Connect-EXOPSSession, or Get-Help Connect-IPPSSession

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Unfortunately, this limits the module's usefulness since we cannot run this in the ISE or on a different Powershell Console.

After some intense googling, binging I found a script that allows you to do just that.

Thanks to Vasil for pointing out that the code below is already in an earlier portion of the thread, Sorry I missed that. :)

Import-Module -Name $((Get-ChildItem -Path $($env:LOCALAPPDATA + '\Apps\2.0\') -Filter Microsoft.Exchange.Management.ExoPowershellModule.dll -Recurse).FullName | ?{ $_ -notmatch '_none_' } | Select-Object -First 1)
$EXOSession = New-ExoPSSession
Import-PSSession -Session $EXOSession -AllowClobber 

You must first install the module as indicated in the reference above.

Let me know if you have any questions.

NOTE: I should point out that I have had issues with this method when using the ISE. When the session has timed out, the ISE locks up when it comes time to prompt for credentials to reauthenticate.

Hi,

You can download the latest MFA enabled Powershell from EAC. It contains the cmdlet name connect-IPPSsession which will connect to S&C.

I contacted Microsoft Support today.  This the response

"I am aware of this limitation however when I checked in our RoadMap site I don’t see any mentioning of this as a coming soon feature. I also checked in our Database and it appears that unlike Exchange online security and compliance current design does not support MFA connection. The suggested work around from engineering is to create one compliance account and use it for that purpose ( do not enable MFA on that account)"